数量遗传学是遗传育种专业领域的重要研究方向。为提高本领域研究生与青年科研人员的基础理论知识、加强学术交流,我们拟举办一系列暑期培训班。第二期主讲教师为来自美国农业部动物基因组与改良实验的Ge (George) Liu教授,欢迎各位研究生和青年科研人员积极报名参加。 一、主办单位 畜禽育种国家工程实验室 农业部动物遗传育种与繁殖重点实验室 畜禽良种产业技术创新战略联盟 中国农业大学动物科技学院 二、主讲人 Prof. Ge (George) Liu Research Biologist (Bioinformatics), Animal Genomics and Improvement Laboratory, USDA, MD, USA 三、培训时间与地点 时间:2017年8月14-15日 地点:中国农业大学动科楼0126(暂定) 四、主要授课内容 1. Biological Sequence Analysis and Mining Genomic Sequence Data 2. Comparative Genomics: Structural and Functional Characterization of the Cattle Genome 3. Structural and Functional Impacts of Copy Number Variations on the Cattle Genome 4. CNV-based Population Genetic Analyses and GWAS in Cattle: What Have We Learned? 5. Functional Annotation of Animal Genomes 五、报名条件 在读研究生和青年科研人员,研究方向为遗传育种学、生物信息学或基因组学。 六、有关事项 1、为了确保授课质量,预计课容60人。申请参加培训的人员请务必于2017年7月31日18:00前通过电子邮件将申请人信息表(EXCEL)发送至ningchao@cau.edu.cn(请注明“数量遗传学培训班-第二期”)。主办单位将根据报名人信息,合理分配不同单位的人员名额。正式名单确认时间为2017年8月3日。 姓名 | 研究生/科研在职人员 | 单位 | 研究方向 | 手机号码 | 邮箱 | 导师姓名(在读研究生填写) | 导师邮箱(在读研究生填写) | | | | | | | | |
2、不收取培训费,学员食宿自理。培训材料只收取版权和成本费,每份500元,参加培训的学员需在动科一楼自行订购。 3、学生报名需经导师同意。上课全勤、考核合格学员将获得由Ge (George) Liu教授签名的学员培训证书。 4、培训人员请加入QQ群638211221,以便获得最新信息。 七、联系人 报名联系人:宁超(在读博士生)15600660761 ningchao@cau.edu.cn 周磊博士 18810408850 zhoulei1112@126.com 地址:北京市海淀区圆明园西路2号中国农业大学西校区动物科技学院,邮编:100193 畜禽育种国家工程实验室 2017年6月28日 附录:Ge (George) Liu教授简介 Education Background 1987-1991 B.S., Nankai University, China 1991-1994 M.S., Nankai University, China 1997-1999 M.C.I.S., Cleveland State University, Cleveland, Ohio, USA 1994-2001 Ph.D., Case Western Reserve University, Cleveland, Ohio, USA Research Experience 2001-2005 Postdoctoral Researcher, Dept. of Genetics & Center for Computational Genomics, Case Western Reserve University, Cleveland, Ohio 2005-pres. Research Biologist (Bioinformatics), GS-13, 14 and 15, Bovine Functional Genomics Laboratory, ANRI, ARS, USDA, Beltsville, Maryland 2009-pres Adjunct Assistant Professor, Associate Professor, and Professor, Department of Animal & Avian Sciences, University of Maryland, College Park, Maryland Accomplishments Pertinent Developed an integrated approach and generated multiple bovine genome-wide CNV maps to study genomic structural variations. Provided proof of CNV's functional impacts on cattle health and production and their contributions to cattle speciation, domestication, and breed formation. Generated the first bovine segmental duplication (SD) map and annotated bovine lineage-specific genes. Optimized genome sequencing methodologies and evaluated the whole genome shotgun approach to finish the human, chimpanzee, bovine and goat genome assemblies. Annotated genomic regions under selective sweep using SNP data. Evaluated sperm DNA methylation and its impacts on male fertility traits. Developed and optimized a phylogentic footprinting tool to identify conserved transcription factor binding sites (TFBS) in mammalian genomes. Career Highlights
With over 20 years of research experience in genetics, bioinformatics and genomics, developed a dynamic and productive research program that utilizes integrated approaches to conduct multidisciplinary research in animal production and health. Published 210 papers and abstracts, which include 45 first and/or corresponding authorships on 75 peer-reviewed publications. 12 of these papers appeared in high-profile journals including Nature, Science, Genome Research and Molecular Biology and Evolution. Supervised high school (5), college (4) graduate (16) students and postdoctoral (4) researchers. Provided critical leadership in developing and applying tools for cattle CNV discovery in major breeds and resulted in 45 invitations to speak at national and international scientific and industry meetings. 5. Played an important role in recognition of the Animal Genomics and Improvement Laboratory as a leading research group in cattle genome research. Contributed to both research and program direction for animal genomics. Genetic variation and marker-assisted selection have become increasingly important research areas for maintaining U.S. competitiveness in the global germplasm market. Publications Dr. Liu has published about 83 publications on Nature, Science, Genome Research, Journal of Biology Chemistry, BMC Genomics, PloS One, Functional and Integrative Genomics, and other journals. Publications (partial) in recent years since 2009 are shown below. Bickhart, D.M., Xu, L., Hutchison, J.L., Cole, J.B., Schroeder, S.G., Song, J., Garcia, J., Van Tassell, C.P., Sonstegard, T.S., Schnabel, R.D., Taylor, J.F., Lewin, H.A., Liu, G. 2016. Whole-genome sequencing reveals the diversity of cattle copy number variations and multicopy genes. DNA Research. 23(3):253-62. Bickhart, D.M., Hutchison, J.L., Xu, L., Schnabel, R.D., Taylor, J.F., Reecy, J.M., Schroeder, S.G., Van Tassell, C.P., Sonstegard, T.S., Liu, G. 2015. RAPTR-SV: a hybrid method for the detection of structural variants. Bioinformatics. 31(13):2084-2090. Bickhart, D.M., Hou, Y., Schroeder, S.G., Alkan, C., Cardone, M., Matukumalli, L.K., Song, J., Schnabel, R.D., Ventura, M., Taylor, J., Garcia, J., Van Tassell, C.P., Sonstegard, T.S., Eichler, E.E., Liu, G. 2012. Copy number variation of individual cattle genomes using next-generation sequencing. Genome Research. 22(4):778-90. Liu G E, Hou Y, Zhu B, et al. Analysis of copy number variations among diverse cattle breeds[J]. Genome research, 2010, 20(5): 693-703.
|